Nano-Structured Demineralized Human Dentin Matrix to Enhance Bone and Dental Repair and Regeneration
نویسندگان
چکیده
منابع مشابه
Liposomal Delivery of Demineralized Dentin Matrix for Dental Tissue Regeneration.
Current dental restorations have short longevity, and consequently, there is a need for novel tissue engineering strategies that aim to regenerate the dentin-pulp complex. Dentin matrix contains a myriad of bioactive growth factors and extracellular matrix proteins associated with the recruitment, proliferation, and differentiation of dental pulp progenitor cells. In this study, we show that de...
متن کاملBone Engineering Using Human Demineralized Dentin Matrix and Recombinant Human BMP-2
We first confirmed the osteoinductive property of human demineralized dentin matrix (DDM) histologically. Human DDM was prepared from vital, extracted teeth and implanted into the subcutaneous tissue in nude mice. The shape of the DDM was a particle type and its size varied from 0.4 to 0.8 mm. The hard tissue induction by 70 mg of the DDM was estimated at 4 weeks after implantation. The DDM ind...
متن کاملDemineralized dentin matrix scaffolds for alveolar bone engineering
From the point of view of implant dentistry, this review discusses the development and clinical use of demineralized dentin matrix (DDM) scaffolds, produced from the patient's own extracted teeth, to repair alveolar bone defects. The structure and the organic and inorganic components of DDM are presented to emphasize the similarities with autogenous bone. Studies of DDM properties, such as oste...
متن کاملCranial bone regeneration according to different particle sizes and densities of demineralized dentin matrix in the rabbit model
BACKGROUND The objective of this study was to place bone graft materials in cranial defects in a rabbit model and compare their bone regenerating ability according to the size and density of demineralized dentin matrix (DDM). METHODS We selected nine healthy male rabbits that were raised under the same conditions and that weighed about 3 kg. Two circular defects 8 mm in diameter were created ...
متن کاملBone Induction by Demineralized Dentin Matrix in Nude Mouse Muscles
PURPOSE This study examined the osteoinductive activity of demineralized human dentin matrix for nude mice. METHODS Twenty healthy nude mice weighing about 15 to 20 g were used for study. Demineralized human dentin matrix was prepared and implanted into the dorsal portion of nude mice (subcutaneous), which were sacrificed at two, four, and eight weeks after demineralized dentin matrix graftin...
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ژورنال
عنوان ژورنال: Applied Sciences
سال: 2019
ISSN: 2076-3417
DOI: 10.3390/app9051013